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Research Projects
Main achievements and ongoing projects
Creation of a severe immunodeficient mice, NOD/Shi-scid, IL-2Rnull
mice (NOD/SCID/IL-2Rnull mice, NOG mice) and development of applications for various animal experimentation and testing systems
Creation of rasH2 mice, in which a human prototype c-Ha-ras oncogene is
introduced, and evaluation of their practical usefulness
A high level of
accuracy
was achieved
in carcinogenicity testing
for drugs and
the
testing period
was reduced
to six months from
the
conventional two years
For more details
about rasH2 mice
Development and establishment of TgPVR mice, in which a human poliovirus
receptor gene is introduced, used
in
safety testing for
oral polio vaccine
Development of a
spinal cord injury model and Parkinson disease model using
common marmosets (new world primates)
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