These five references are selected from among more than 320 references. Reference 1 explains the importance of the new concept of the  “dramatype”, which is an  important factor for obtaining a reproducibility of physiological response to experimental procedures. Reference 2  stresses the significance of a quality assurance system for experimental animals that led to the establishment of ICLAS Monitoring Center. References 3, 4 and 5 describe three representative animal models  that have contributed to biomedical science worldwide; References 3 and 4 for the polio eradication  program of the World Health Organization; Reference 3 for short-term carcinogenicity testing in ILSI/HESI ACT  Study with the National Institute of Environmental Health Sciences; Reference 5 for the current status and future prospects of developing humanized mice.

Ministry of Education Scientific Research Grant for Special Research (1) Report of research on preparation of quality standards and establishment of test methods for laboratory animals, 1980.

T. Nomura et al. Development of transgenic animals as human disease models: Special topic overview. Laboratory Animal Science, Vol.47,113-126, 1997.

E. Dragunsky, T. Nomura, K. Karpinski, J. Furesz, D. J. Wood, Y. Pervikov, S. Abe, T. Kurata, O. Vanloocke, G. Karganova, R. Taffs, A. Heath, A. Ivshina, and I. Levenbook. Transgenic mice as an alternative to monkeys for neurovirulence testing of live oral poliovirus vaccine: validation by a WHO collaborative study; Bulletin of the WHO, 81, 251-260, 2003.

T. Nomura, N. Tamaoki, A. Takakura, and H. Suemizu. Basic Concept of Development and Practical Application of Animal Models for Human Diseases, In: Humanized Mice; Current topics in Microbiology and Immunology (Eds: T. Nomura, T. Watanabe, and S. Habu), pp1-22. Springer-Verlag. Berlin and Heidelberg, 2008.